Boris Johnson’s new cabinet will meet for the first time later, following a reshuffle that saw Sajid Javid quit his role as chancellor.
The prime minister had offered to reappoint Mr Javid on the condition he fire his team of aides – a demand rejected by Mr Javid on Thursday.
Rishi Sunak, former chief secretary to the Treasury, said he had “lots to get on with” after replacing Mr Javid.
Andrea Leadsom and Esther McVey are among others no longer in government.
Both women, along with Mr Javid, had been among the contenders in the Conservative leadership contest last July that was won by Mr Johnson.
Mr Javid, who had been due to deliver his first Budget in March, said he was left with “no option” but to resign because “no self-respecting minister” could accept the prime minister’s demands.
His departure from the cabinet follows rumours of tension between Mr Javid and the prime minister’s senior adviser, Dominic Cummings.
In his resignation letter, Mr Javid said: “I believe it is important as leaders to have trusted teams that reflect the character and integrity that you would wish to be associated with.”
Downing Street said there would now be a joint team of economic advisers for both the chancellor and prime minister.